White Powder Lidocaine 99% Purity Local Anesthesia Drugs Procaine
Base Pain Killer Lidocaine Powder CAS 137-58-6
|Product Name||Lidocaine Hydrochloride|
|Synonyms||Lidocaine HCL; Lidocaine HCI;
|Product Categories||API;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Research Chemical;Pharma materials|
|Appearance||White crystalline powder|
|Usage||Local anesthesic;Na+ channel blocker; Anesthetic (local); antiarrhythmic (class IB). Long-acting,
membrane stabilizing agent against ventricular arrhythmia.
Originally developed as a local anesthetic.|
1. Lidocaine hydrochloride is a white powder without smell and with
a bitter taste that is used both in human and veterinary medicine.
The drug is also known as lignocaine hydrochloride, and is used as
a local anesthetic and to regulate certain medical problems related
to heart rhythm. Injections of it are used to provide local
anesthesia during various minor surgical procedures. It is also
available in various topical preparations, such as gels, sprays,
creams, and ointments that are usually applied to the skin or the
mucous membranes. This drug was first manufactured in Sweden in
1943 and was then named xylocaine.
2. When used for anesthetic purposes, lidocaine hydrochloride works
by blocking certain functions of the nervous system, inhibiting the
transmission of pain impulses from the treated area to the brain.
It is a fast-acting form of local anesthesia that often starts to
work within five minutes. The effects wear off in a relatively
short time, often a couple of hours, because the drug is quickly
metabolized by the liver.
1. Lidocaine Hydrochloride,The efficacy profile of lidocaine as a
local anesthetic is characterized by a rapid onset of action and
intermediate duration of efficacy . Therefore, lidocaine is
suitable for infiltration , block , and surface anesthesia .
Longer-acting substances such as bupivacaine are sometimes given
preference for subdural and epidural anesthesias ; lidocaine ,
though , has the advantage of a rapid onset of action .
2. Lidocaine Hydrochloride, (adrenaline) vasoconstricts arteries ,
reducing bleeding and also delays the resorption of lidocaine ,
almost doubling the duration of anaesthesia . For surface
anesthesia, several available formulations can be used for
endoscopies , before intubations , etc . Buffering the pH of
lidocaine makes local numbing less painful . Lidocaine drops can be
used on the eyes for short ophthalmic procedures . There is
tentative evidence for topical lidocaine for neuropathic pain.
Lidocaine HCI Test Report(COA):
|Characteristics||A white or almost white crystalline powder||Conform|
|Identification||Should meet related requirements||Conform|
|Appearance of solution||Should meet related requirements||Passed|
|Specific optical rotation||+135~+150||+143|
|Boiling point||350.8 C at 760 mmHg||Conform|
|Flash point||166 C||Conform|
|Lincomycin B||5.0% max||2.9%|
|Heavy metals||5ppm max||Conform|
|Residue on ignition||0.5% max||0.1%|
|Bacterial endotoxins||smaller than 0.5IU/mg||smaller than0.5IU/mg|
|Assay||Not less than 89.5% and not more than 102.0% of lincomycin
1. This medication is used on the skin to stop itching and pain
from certain skin conditions (e.g., scrapes, minor burns, eczema,
insect bites) and to treat minor discomfort and itching caused by
hemorrhoids and certain other problems of the genital/anal area
(e.g., anal fissures, itching around the vagina/rectum).
2. Some forms of this medication are also used to decrease
discomfort or pain during certain medical procedures/exams (e.g.,
sigmoidoscopy, cystoscopy). Lidocaine is a local anesthetic that
works by causing temporary numbness/loss of feeling in the skin and
Local Anesthetic Products:
|Bupivacaine hydrochloride||CAS: 14252-80-3|
|Levobupivacaine hydrochloride||CAS: 27262-48-2|
|Lidocaine hydrochloride||CAS: 6108-05-0|
|Pramoxine hydrochloride||CAS: 637-58-1|
|Procaine hydrochloride||CAS: 51-05-8|
|Propitocaine hydrochloride||CAS: 1786-81-8|
|Ropivacaine hydrochloride||CAS: 132112-35-7|
|Tetracaine hydrochloride||CAS: 136-47-0|
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